2. The Jaguars defense will register 2 turnovers vs. the Saints
The Jaguars' defense has put an emphasis on creating turnovers this season. Linebacker Foyesade Oluokun recently said finishing the 2022 season strong has motivated the group to generate as many takeaways as possible. Right now, Jacksonville leads the NFL with 15. Andre Cisco, Rayshawn Jenkins, and Darious Williams each have three, tied for the league's lead.
The defense should take advantage of the Saints' injury woes and an inconsistent Derek Carr and come out of the game with a couple more turnovers. On top of that, they'll limit the New Orleans rushing game to fewer than 50 yards, whether Jamaal Williams, who is listed as questionable, suits up or not.
1. The Jaguars offense will score 30 points with or without Trevor Lawrence
One of the biggest plotlines surrounding Thursday Night Football is whether Trevor Lawrence will suit up or not. If he doesn't, it will be the first time in his NFL career he'll miss a game. At this point, it looks like a toss-up, with Jacksonville signing preseason star Nathan Rourke to the active roster as insurance.
But even if Lawrence isn't behind center Thursday, the Jags have more than enough weapons on offense to move the ball and visit the Saints' end zone several times. Although wide receiver Zay Jones has already been ruled out for the game, whoever starts at quarterback will have a pair of capable targets in Christian Kirk and Calvin Ridley.
Add the presence of tight end Evan Engram and the running game, and the offense will have lots of opportunities to finish the game with more than 30 points for the third time this season.