Jaguars vs. 49ers game today: Time, Location, Streaming, Odds, Injury Report & More

In their first home at EverBank Stadium since Week 3, the Jacksonville Jaguars will face the San Francisco 49ers. While they've gone 4-0 on the road this season, they're 2-2 at home and one of those games was in London, so technically, the last time they won at the Bank was in the opener when they beat the Indianapolis Colts. Yikes!

Leaving aside technicalities, the 49ers have lost three in a row while the Jaguars are sitting on a five-game winning streak. That won't make the game any easier though. San Francisco has been a perennial contender the past few seasons and has enough playmakers on both sides of the ball to beat the Jags. With that in mind, here's everything you need to know for Sunday's bout.

Jaguars vs. 49ers Injury Report for Week 10

The Jaguars have ruled out wide receiver Zay Jones for Week 10. Jones has been dealing with a knee injury the past few weeks and has only suited up for three games this season. He returned to practice on a limited basis this week but will most likely need more time before he's able to contribute. On the other hand, Jacksonville will get Walker Little back for the game.

Little suffered an MCL injury in Week 5 and has sat out the last three games. He didn't appear on the team's injury report, so he'll get the start at left guard. Cornerback Tyson Campbell and safety Andre Cisco got the questionable tag for the game but there's a strong chance they'll both be available for the game.

Head coach Doug Pederson met with the local media Friday and said Campbell and Cisco, along with Little, did well in practice, so they should return barring a setback. Safety Daniel Thomas also popped up on the Injury Report with a hamstring injury.

The 49ers, for their part, have already ruled out left guard Aaron Banks and listed Trent Williams (ankle), linebacker Dre Greenlaw (shoulder), and Defensive end Robert Bael Jr. (hamstring) as questionable. Defensive end Drake Jackson had originally been ruled out for Week 10 but he's since been placed on Injured Reserve.

Jaguars vs. 49ers Odds/Spread for Week 10

Surprisingly, the Jaguars are a 3-point underdog even though they're the home team. Their moneyline sits at +145, per BetMGM. Place a bet of $100 and win $145 for a total payout of $245 if they beat San Francisco. The Niners' moneyline is -167. To win $100, bet $167 yards for a payout of $267. The over/under for the game is set at 44.5 points.

How to watch/listen to the Jaguars vs. the 49ers in Week 10

Kickoff will be at 1:00 p.m. ET/ 10:00 a.m. PT, and the broadcast will be on Fox 30. Joe Davis and Daryl Johnston will provide live commentary while Pam Oliver handles sideline duty.

You can listen to the game on WJXL 92.5 FM/1010 AM or 99.9 Gator Country. Frank Frangie, Jeff Lageman, and Tony Boselli will be the booth analysts while Bucky Brooks reports from the sidelines. It will also be available on Sirius Radio, internet channel 814, feed channel 230.

Jaguars vs. 49ers stream for Week 10

If you're looking for a stream, try fuboTV. All you need is an internet connection to get started and catch the game on your phone, tablet, or PC. Click here for your free seven-day trial.

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