Jaguars vs. 49ers final injury report: Walker Little ready to go, Zay Jones ruled out

The Jacksonville Jaguars will get einforcements when they welcome the San Francisco 49ers Sunday. Offensive lineman Wallker Little is good to go after missing the last three games. Also, there's a chance both cornerback Tyson Campbell, and safety Andre Cisco suit up despite the fact that they're listed as questionable on the team's final injury report. On the other hand, wide receiver Zay Jones has been ruled out.

Head coach Doug Pederson met with the local media Friday and said Jones was a long shot to play, so his status for Week 10 doesn't come as a surprise. Earlier this week, Pederson said the Jags weren't ruling out placing Jones on Injured Reserve but he's returned to practice, albeit in a limited basis, so it no longer seems like an option. That said, it will be a couple of weeks before he's a full-go.

Pederson also told the media that Littlle, Campbell and Cisco had a good week of practice. Then again, Cisco and Campbell still managed to land on the Injury Report. This may be cautionary though, and barring any setbacks, they should both play.

The recently acquired Ezra Cleveland also appeared on the Injury Report. He's been dealing with a foot strain for a while but he says he's close to 100 percent. A second-round pick, Cleveland played 53 games with 49 starts for the Minnesota Vikings before being traded to the Jags at the deadline. With Walker Little slated to start at left guard, Cleveland will be the team's primary backup inside.

On a similar note, San Francisco listed left tackle Trent Williams as questionable but ruled out offensive guard Aaron Banks, so their offensive line could be without two starters Sundays. Here's the Jaguars' full injury report.

Having Walker Little back in the fold is huge for the Jacksonville Jaguars in Week 10

Walker Little began the 2023 season at left tackle but moved inside after Cam Robinson's return from a four-game suspension for violations to the league's performance-enhancing drug policy. However, Little suffered a knee injury in the game he lined up at guard. Having him back in Week 10 will allow the Jaguars to contain a stout 49ers defensive line that includes Nick Bosa, Chase Young, Arik Armstead and Javon Hargrave.

On the other hand, Andrew Wingard and Montaric Brown have good job filling in for Andre Cisco and Tyson Campbell, respectively, but having all hands on deck should allow the Jacksonville secondary to contain wide receivers Deebo Samuel, Brandon Aijuk and multi-purpose running back Christian McCaffrey, who can create mismatchups by lining up in the slot.

Winning this game will be key for the Jacksonville Jaguars. They need to fend off a Houston Texans team that isn't out of the division race and could get hot in the second half of the season. Also, beating the San Francisco 49ers will ensure that the Jags keep up with other teams in the AFC and get the best possible seeding in the playoffs.

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