One storyline to keep an eye on in Week 4 is whether Dyami Brown will suit up. The Jacksonville Jaguars have provided much information about the veteran receiver's availability for the game, but based on the latest injury report, he has a chance to suit up against the San Francisco 49ers.
Alivia Tassely of Action Sports Jax reported that Brown participated in Thursday's practice after sitting out Wednesday's. He earned a limited designation on the injury report.
Aside from Brown, running back Bhayshlu Tuten (shoulder), left guard Ezra Cleveland (ankle), right guard Patrick Mekari (elbow), and offensive lineman Wyatt Milum (knee) were listed as limited. Below is the full injury report:
Thursday Injury Report pic.twitter.com/fcRjqKM40w
— Jacksonville Jaguars (@Jaguars) September 25, 2025
On the 49ers' side of things, guard Connor Colby (groin), defensive tackle Kalia Davis (defensive tackle), cornerback Renardo Green (neck), and quarterback Brock Purdy popped up on the injury report with the limited participant status. Defensive end Yetur Gross-Matos, wide receiver Jauan Jennings (ankle, shoulders),
Related: 3 critical storylines to keep an eye on vs. the 49ers in Week 4
The Jaguars would love to have Dyami Brown around (but only if he's healthy)
A third-round pick by the Washington Commanders in the 2021 draft, Brown had an underwhelming start to his NFL career but put it all together last season. He signed a one-year, prove-it deal with the Jaguars in free agency and has quickly turned into a key cog on offense, logging 10 receptions for 116 yards with one touchdown in three games.
Not having Brown for Week 4 would be a massive blow for the Jaguars. That said, Parker Washington, Travis Hunter, and Tim Patrick will be ready to step up during his potential absence.
Sure, head coach Liam Coen said that Hunter's role on offense won't change in spite of the injuries in the position. The reason is that Jacksonville doesn't want to put too much on his plate. However, Washington and Patrick would most likely see an uptick in playing time against the 49ers. In fact, both of them saw an expanded role in Week 3 once Brown went down.
Now, there's a chance Brown will play against San Francisco. Having him around would surely increase their odds of coming out on top. That said, the team's brass will surely err on the side of caution and ultimately hold him out if he isn't good to go.
In the end, the Jaguars still have a bit of time to decide whether Dyami Brown will play in Week 4. The final injury report will bring clarity to the situation, but the fact that he was able to practice Thursday is most definitely a step in the right direction.