Jaguars WR Calvin Ridley gets 100+ yards vs. 49ers: 5 bold predictions for Week 10

4. The Jaguars pass rush duo of Josh Allen and Travon Walker will combine for 4 sacks

Outside linebacker Josh Allen is having a banner year while Sophomore Travon Walker already has as many sacks as he had last year (3.5) and should keep getting better as the season progresses. The duo will go against a San Francisco offensive line that could be without left tackle Trent Williams and left guard Aaron Banks.

Even if both Williams and Banks play, the Jags' pass rush stacks up favorably against the 49ers offensive line. They got DaVon Hamilton back before their BYE. Hamilton began the season on Injured Reserve and returned to the team in Week 8. He'll help Allen and Walker bring the heat and sack Brock Purdy four times between the two.

3. Jaguars RB Travis Etienne will run for 100+ yards and 2 TDs vs. 49ers

There are a couple ways to look at Travis Etienne's performance in 2023. On the one hand, he's averaging 3.9 yards per carry, 1.2 yards less than last year. On the other hand, he's among the rushing leaders in the NFL and is tied with Christian McCaffrey for the most broken tackles with 33. Moreover, he's averaging 106 yards from scrimmage this season.

Simply, Etienne is a big part of the Jaguars' offensive identity. In Week 10, he'll go against a 49ers' rushing defense that has surrendered 122 yards on the ground the last three games. This should incentivize Jacksonville to feed Etienne the ball.