Jaguars spoil Colts QB Gardner Minshew homecoming in Week 6: 5 bold predictions

4. Jaguars CB Darious Williams will have an INT for the third game in a row

Cornerback Darious Williams was off a rough start last year but he fared much better once he moved to the perimeter, where's better suited to play. Although he logged a team-high 16 pass deflections, he didn't register an interception.

Having gotten familiarized with defensive coordinator Mike Caldwell's scheme, Williams has improved in Year 2. He's already registered two picks in 2023, one returned for a touchdown and the other one with the game on the line in Week 5. Although the Florida native made a few mistakes early in the season, he's made enough plays to make up for it.

Right now, Williams is among the Jaguars' top performers in the defensive backfield and he'll continue to make plays, including an interception against the Colts in Week 6.

3. The Jaguars will keep Jonathan Taylor and Zach Moss under 100 yards in Week 6

After a subpar performance in the opener, the Colts running game has been operating at full steam, averaging 147 rushing yards per game the last four weeks. That was mostly without Jonathan Taylor, who spent four games on Injury Reserve. With him back in the mix, Indy has a 1-2 punch at running back, one they'll try to use as much as possible in Week 6.

However, the Jaguars have done a good job of stopping the run this season and they will be unfazed by the duo of Taylor and Zach Moss. In fact, the return of Dawuane Smoot to the lineup will allow the defensive front to keep the Colts' running game under 100 yards and no touchdowns in Week 6.