Jaguars OLB Josh Allen pulls hat trick vs. Bills: 5 bold predictions for Week 5

No. 4 Jaguars safety Andre Cisco will have a pick-6 in Week 5

Third-year safety Andre Cisco has had a breakout year in 2022. Already, he's snagged two picks, including one against the Falcons in Week 4. Following the game, he jokingly said that he was going to talk to god and find out what the deal was with him and the end zone.

Regardless of what happened last week, Cisco will get an interception and take it to the house. On top of that, he'll force a fumble. He's already got two picks and one forced fumble this season. He'll have a strong chance to increase the tally against the Bills.

No. 3 Jaguars RT Anton Harrison won't give up a single sack vs. the Bills in Week 5.

The Jaguars' decision to draft Anton Harrison 27th overall in April didn't look so great early in the season. However, you need time to assess how good (or bad) a selection will be and a three-game sample is simply too small.

Harrison was aware of his early struggles and has put in the work to ensure he becomes the player the Jags thought they were getting when they picked him. In Week 4, he didn't allow a single sack and posted his best Pro Football Focus pass-blocking grade yet.

Rookies always will experience ups and downs but Harrison should be able to build on last week's encouraging performance. Even though he's facing the daunting task that is the Bills defensive front, he should be up to the task.