No. 4 Jaguars player who must shine vs. the Bills: Travis Etienne, RB
The Jaguars have struggled to establish the run this season but this is by no means Travis Etienne's fault. See, the former Clemson Tiger is still the dynamic playmaker who totaled over 1,400 yards from scrimmage last year. However, he's had a hard time finding openings across the line of scrimmage.
Against the Falcons, Jacksonville didn't abandon the run but they didn't do a great job either, tallying 105 yards as a team. While those numbers don't necessarily look bad, 42 of those yards came in two plays in which Trevor Lawrence left the pocket. The Bills' defense is much better than Atlanta's. Yet, Doug Pederson will put an emphasis on pounding the ball.
"Travis is a really good running back and we trust what he does. Against a team like this, he got to try at least to run the football a little bit. You can't just drop back and throw it every down or they're gonna get you," Pederson said.
If the Jags can do a decent job of running the ball against the Bills, their chances of winning will go a bit up.
No. 3 Jaguars player who must shine vs. the Falcons: Anton Harrison, RT
The Bills have one of the most stacked defensive fronts in the NFL, so the Jaguars' offensive line cannot afford to lose the battle of the trenches. In particular, Rookie Anton Harrison must build from last week's performance.
Harrison, the 27th overall pick in this year's draft, struggled the first three weeks of the season. However, he played much better against the Falcons, giving up no sacks or pressures. On top of that, his Pro Football Focus pass-blocking grade of 75.4 was the best one he's posted this season.
The Bills aren't lacking pass rushers, so Harrison and the rest of the offensive line must do their part to ensure Trevor Lawrence has good protection and Travis Etienne has room to run.