Odds and bold Jakobi Meyers prediction for the Jaguars finale vs. the Titans

• The Jags are gearing up for the season finale.
Jacksonville Jaguars wide receiver Jakobi Meyers (3) rushes for yards against New York Jets cornerback Qwan'Tez Stiggers (37) during the first quarter of an NFL football matchup at EverBank Stadium, Sunday, Dec. 14, 2025, in Jacksonville, Fla.
Jacksonville Jaguars wide receiver Jakobi Meyers (3) rushes for yards against New York Jets cornerback Qwan'Tez Stiggers (37) during the first quarter of an NFL football matchup at EverBank Stadium, Sunday, Dec. 14, 2025, in Jacksonville, Fla. | Corey Perrine/Florida Times-Union / USA TODAY NETWORK via Imagn Images

The Jacksonville Jaguars keep getting hot to finish the regular season. Just one week after trouncing the Denver Broncos, they took care of business when they disposed of the Indianapolis Colts. Next on their schedule are the 3-13 Tennessee Titans.

Back when the NFL announced this AFC South to end the year, it looked like it was going to have huge ramifications, and it kind of does, but only for the Jags. After all, Tennessee was eliminated from playoff contention a while back. Then again, they'll have a chance to play spoilers in Week 18, and the teams will surely hope the Titans pull off the upset.

Although Jacksonville has already clinched a playoff spot, the seeding has yet to be determined. Based on how things unfolded in the finale, the Jags could get as high as the top seed or as low as the seventh. Of course, they'll put most of the guesswork away by defeating Tennessee.

If the Jags win in Week 18, they'll most likely be the No. 3 seed, so they could have home-field advantage in at least two rounds of the playoffs. For that reason, they cannot afford to put their guard down in the finale. With this in mind, here are the odds and a bold prediction for this AFC South showdown.

Odds and spread for the Jaguars game vs. the Titans in Week 18

The Jaguars are a 12.5-point favorite with a moneyline of -850. Place a wager of $850 to win $100 for a total payout of $950 if they beat Tennessee. The Titans' moneyline sits at +575. Bet $100 and win +575 for a payout of $675 if they defeat Jacksonville. The over/under for the game is set at 47.5.

Keep in mind that the odds are periodically refreshed, so they can change at any moment.

Related: Rich Eisen explains the Jaguars may not reach their ceiling until 2026

Bold Jakobi Meyers prediction for the Jaguars game vs. the Titans in Week 18

Parker Washington is rightly the talk of the town after logging over 100 receiving yards in back-to-back weeks. However, he's far from the only receiver who's come through for the Jags. Jakobi Meyers hasn't gotten nearly as much attention (from the national media and opposing teams). However, he remains his same reliable self, hauling in 10 receptions for 84 yards in the same snap.

By now, Washington has already caught the Titans' attention, so they'll try to do their best to neutralize him. The issue with containing him is that Trevor Lawrence has no shortage of weapons in his arsenal.

If Tennessee brackets Washington, No. 16 will simply look somewhere else. And given how quickly his connection with Meyers has grown, expect him to target him several times throughout the game. The Titans won't have an answer for him. This, in turn, will lead to the former North Carolina State Wolfpack's first 100-yard game of the season.

Bold prediction: Jakobi Meyers registers nine receptions for 120 yards with two touchdowns.

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